Monthly Archives: September 2017

Treating Metastatic Breast Cancer with Olaparib

Olaparib (Lynparza) is a treatment for advanced ovarian cancer in patients carrying inherited mutations in the BRCA gene. A study compares olaparib with standard drugs for the treatment of metastatic breast cancer in patients with inherited BRCA mutation. Mutations in BRCA1 and BRCA2, the tumor suppressor genes that code for proteins involved in DNA repair,…

Comparing Nivolumab and Chemotherapy as Treatments for Non-Small-Cell Lung Cancer

Comparing the effectiveness of an immunotherapy inhibitor, nivolumab, with platinum-based chemotherapy may help oncologists determine which drug is most beneficial as a first line treatment for patients with advanced or recurrent non-small-cell lung cancer. As its name suggests, platinum-based chemotherapy contains complexes of the metal platinum, which can bring along an entourage of symptoms. Though…

Curcuma Herb Essential Oils: Composition and Therapeutic Activity

The essential oils found in Curcuma herbs have many uses. Researchers in China determine the composition and therapeutic activity of Curcuma herb essential oils extracted from four Curcuma herb species. Curcuma herbs have been used in Southeast Asia for thousands of years for their claimed antioxidative, antimicrobial, anti-inflammatory, and cytotoxic effects. the chemical composition of…

Comparing Treatment Programs for Opiate-Dependent Individuals

Given that the vast majority of opiate-dependent individuals relapse soon after detoxification, a recent study investigated whether the use of medications could assist in reducing the severity of opiate withdrawal. With over 11 million heroin users worldwide, the global health burden of opiate-dependent individuals remains high. Opiates are a class of drugs (including illicit drugs…

Does Learning Two Languages Positively Impact Brain Function?

Being bilingual has been shown to be related to changes in brain structure and function and may positively affect cognitive control processes. A recent study determines whether learning two languages at the same time positively impacts cognition. Several studies have demonstrated the impact of learning two languages on brain structure and function. Most of these…

Will Proper Geriatric Assessments Lead to Reduced Admission Rates?

A recent analysis of geriatric patients hospitalized through emergency departments shows that proper geriatric assessments of older patients may reduce admission rates. A recent article published in Age and Ageing by the Oxford University Press reviewed the evidence behind performing comprehensive geriatric assessments (CGA) for more elderly patients that present at the emergency department. The…

How does the Sp3-HDAC2 Complex Reduce Synaptic Function in Alzheimer’s?

In a recent study, researchers sought to identify proteins important for the anti-neural plasticity effects of histone deacetylase 2 (Hdac2) in Alzheimer’s disease. How Cells Control Gene Activity Acetylation is one method by which cells control gene activity by the addition or removal of acetyl groups. Acetylation is performed by enzymes called acetyltransferases on histone…